For patients with higher WBC levels, the most important predictor of EFS was blastcell expression of THY antigen.
2
The introduction of this new blastcell definition in a larger series of patients is recommended to confirm these preliminary observations.
3
These "blast " cells demonstrate a significant ability for the generation of secondary colonies of multiple lineages, including additional blastcell colonies.
4
The variables associated with improved long term DFS were a bone marrow blastcell count less than 20% and an intensified conditioning regimen.
5
At the initial diagnosis, the blastcell morphology and immunophenotype were consistent with the diagnosis of typical ALL (L1 subtype according to FAB classification).